Diagnosis is based on clinical, histopathologic, and photobiologic features. Actinic keratosis is seen in fairskinned persons on skin areas that have had longterm sun exposure. Nuclear contour index helps differentiate actinic reticuloid. Pdf file of the complete article 242k, or click on a page image below to browse page by page. The photosensitivity dermatitis and actinic reticuloid syndrome. One of the distressing conditions of actinic reticuloid ar is its persistence for long durations without any demonstrable contact with the phot. Chronic actinic dermatitis, synonymous with the photosensitivity dermatitis and actinic reticuloid syndrome, presents as a dermatitis andor a.
Actinic reticuloid is a rare chronic idiopathic photosensitive dermatosis belonging to the spectrum of chronic actinic dermatitis and may be mistaken for cutaneous tcell lymphoma. Differentiation between actinic reticuloid and cutaneous t cell. Chronic actinic dermatitis is a chronic photodermatosis that occurs most commonly in men in their 60s and 70s. Chronic actinic dermatitis a study of clinical features somani vk. Actinic reticuloid with transition to photosensitive eczema and return to actinic reticuloid serrano sanmiguel g, bonillo. Arch dermatol 1994 chronic actinic dermatitis cad is an idiopathic photosensitivity characterized by an eczematous photoeruption, a lowered minimal erythema dose to uvb radiation, and histologic findings of.
Links to pubmed are also available for selected references. In the eye, the cornea, in particular, but also the lens and retina are most. Perelman department of dermatology, new york university abstract. Chronic actinic dermatitis cad, also known as the persistent. Chronic actinic dermatitis cad, one of the immune mediated photodermatoses, comprises a spectrum of. Health, general photosensitivity disorders care and treatment case studies diagnosis sezary syndrome. Actinic radiation article about actinic radiation by the. Chronic actinic dermatitis an overview sciencedirect topics. Chronic actinic dermatitis with vitiligolike depigmentation. Diverentiation between actinic reticuloid and cutaneous t cell. In patients suspected of having actinic reticuloid, application of both techniques.
Actinic reticuloid with transition to photosensitive eczema and return to actinic reticuloid serrano. Disseminated superficial actinic prokeratosis icd10cm diagnosis code l56. Department of dermatology, free university hospital, amsterdam, netherlands. Chronic actinic dermatitis a study of clinical features. A 54yearold man suffered from a chronic dermatitis that was more severe on lightexposed areas. A 52yearold man experienced a pruritic and erythematous eruption on his face, neck, upper chest, and arms. Because cells from pho tosensitivity dermatitis actinic reticuloid patients show in creased sensitivity towards oxidative stress but show no sig nificant change in oxidant activation of the heme oxygenase. It is characterised by severely itchy, red, inflamed, and thickened dry skin, mainly in areas that have been exposed to sunlight or artificial light. Magnus b a paediatric research unit, guys hospital medical school, london se1 9rt, united kingdon b department of photobiology, institute of dermatology, london e9 6bx, united kingdon fibroblasts cultured from six patients with actinic reticuloid ar. C 811 cryosurgery is an effective modality for treating solitary or multiple actinic keratoses. Cad is classically thought to be primarily a disease of elderly caucasian males, though recent evidence suggests that in skin of color, the disease manifests more often in younger females. It is often treated because it might turn into squamous cell skin cancer.
Light testing with a monochromator showed abnormal photosensitivity to both short and longwave ultraviolet light as well as to the violet, blue, and green wavelengths of visible light. Arch dermatol 1995 actinic reticuloid is a chronic photosensitivity dermatosis that can lead to erythroderma. May 09, 2017 actinic prurigo ap is a chronic, pruritic skin disease caused by an abnormal reaction to sunlight. It is considered precancerous or an early form of cutaneous squamous cell carcinoma a keratinocyte cancer. Actinic keratosis is usually considered to be a precancer. Chronic actinic dermatitis lesley clarkloeser md dermatology online journal 94. Differentiation between actinic reticuloid and cutaneous t cell lymphoma can be extremely difficult. Actinic reticuloid, international journal of dermatology 10. Request pdf reticuloide actinico actinic reticuloid is a chronic photodermatosis which is typical of elderly patients and that is characterized by the presence of papules and. Clinical report by acta dermatovenerologica alpina, pannonica et adriatica. Apr 10, 2020 chronic actinic dermatitis cad is a photosensitivity disorder defined by a persistent eczematous reaction of 3 months or greater duration on sunexposed body parts, abnormally low phototest. We have concluded that not all the patients are persistent light reactors and that the histologic presentation can be quite variable, in some. This article describes two patients suffering from cad with widespread vitiligolike lesions.
Get a printable copy pdf file of the complete article 1. Actinic reticuloid imitating sezary syndrome article pdf available in acta dermatovenerologica alpina, panonica, et adriatica 2. Increasing experience indicates that these syndromes table, which were defined 15 or more years ago and generally occur in elderly men, represent arbitrary, confusing, and largely unnecessary. Chronic actinic dermatitisactinic reticuloid cadar is an eczematous hypersensitivity reaction to ultraviolet rays that can vary from mild eczematous cases to ar, the most severe cases which. Disseminated superficial actinic porokeratosis dsap disseminated superficial actinic porokeratosis. Actinic reticuloid and actinic granuloma short description. We report four cases of actinic reticuloid, including the first case ever reported in a woman.
Actinic keratosis is a scaly spot found on sundamaged skin. Chronic actinic dermatitis is a rare skin condition that mainly affects men over the age of 50 years. Pdf actinic reticuloid ar or chronic actinic dermatitis is considered a sunlight induced pseudolymphoma psl on. Differentiation between actinic reticuloid and cutaneous t. Diagnosis and treatment of chronic actinic dermatitis request pdf. Diagnostic criteria were laid down about 20 years back, but clinical features are the mainstay in diagnosis. The features of this patients disease indicate actinic reticuloid. Skin biopsy specimens revealed histopathologic findings. The unifying term cad comprises such diseases as persistent light reactions, chronic photosensitivity eczema and actinic reticuloid which have clinical and pathogenetic similarities. Pdf actinic reticuloidphotosensitivity or pseudolymphoma. Chronic actinic dermatitis cad is persistent light reactivity encompassing actinic reticuloid and photosensitive eczema. Jan 23, 2020 actinic keratosis ak is a uv lightinduced lesion of the skin that may progress to invasive squamous cell carcinoma. Sep 11, 2012 chronic actinic dermatitis is a condition involving abnormal cutaneous photosensitivity to uv and, often, visible wavelengths.
Actinic reticuloid is a chronic multifactorial dermatitis with severe photosensitivity, which histologically mimics epidermotropic cutaneous tcell lymphoma. Chronic actinic dermatitis also known as actinic reticuloid, chronic photosensitivity dermatitis, persistent light reactivity, and photosensitive eczema. Chronic actinic dermatitisactinic reticuloid request pdf. It usually presents as a dermatitis that maximally, but not exclusively, affects photo. Chronic actinic dermatitis actinic reticuloid cadar is an eczematous hypersensitivity reaction to ultraviolet rays that can vary from mild eczematous cases to ar, the most severe cases which may resemble cutaneous tcell lymphoma. Recalcitrant chronic actinic dermatitis treated with lowdose. Pdf actinic reticuloid presented as facies leonine. Actinic reticuloid actinic reticuloid guardiola, armando. Free full text similar articles actinic reticuloid. The production of chemical changes in a substance upon which electromagnetic radiation is incident explanation of actinic radiation. Actinic keratosis is often treated with either cryotherapy or topical creams or gels. Jul 31, 20 dermatopathology reference describes actinic reticuloid histopathology including histologic features and provides links to additional medical references.
Chronic actinic dermatitis associated with adult tcell. To update readers on the current understandings of chronic actinic dermatitis cad in regard to epidemiology, clinical findings, pathophysiology, treatment, and prognosis. But because this risk is low, treatments are generally aimed at avoiding scars or other disfiguring marks as much as possible. It is rare, but more common in the elderly than in younger populations, with an estimated prevalence of one in 2000 in the. Actinic keratoses should be treated because of their potential to progress to squamous cell carcinomas. Chronic actinic dermatitis in the elderly springerlink. Actinic reticuloid definition of actinic reticuloid by. Persistent light reactivity, photosensitive eczema, photosensitivity dermatitis, or actinic reticuloid.
Actinic definition of actinic by medical dictionary. Demonstration of clonal t cell receptor tcr gene rearrangements has been suggested as a potential diagnostic criterion, but the results obtained thus far have been conflicting. Reticuloid definition of reticuloid by medical dictionary. It occurs in patients of all ethnic groups, but in the united states, it is more commonly seen in darkskinned individuals.
Actinic reticuloid ar is a chronic persistent photosensitive dermatosis of elderly men, described first by ive and coworkers in 1969 it is clinically characterized by pruritic infiltrated papules and plaques on exposed parts with occasional extension to covered areas and rarely associated with episodes of erythroderma. Actinic keratoses affect people that have often lived in the tropics or subtropics and have predisposing. A case of chronic actinic dermatitis that responded. Chronic actinic dermatitis cad, one of the immune mediated photodermatoses, comprises a spectrum of conditions including persistent light reactivity, photosensitive eczema and actinic reticuloid.
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